to explore right ventricular diastolic function by echocardiography and invasive hemodynamic study in patients with Wolf-Parkinson-White syndrome (WPW).Method
We included into the study 70 patients with cardiac arrhythmias. Patients were 6 — 29 years old (median — 14 yrs, lower quartile — 11 yrs, upper quartile — 16 yrs). 35 of patients of them (50%) were male and 35 of patients were female (50%). In the main group we included patients with WPW. In the comparison group we included 23 patients with paroxysmal atrioventricular (AV) nodal reciprocal tachycardia. Right ventricular (RV) diastolic function (DF) has been evaluated by echocardiography (was performed in all patients) and by invasive hemodynamic study, which has been performed in 26 patients in the main group before EP study and after 40 minutes of RFCA of AP and in 9 patients in the comparison group before EP study and after 40 minutes of RF modulation of AV nodal conduction. Invasive hemodynamic study included: determine of end-diastolic pressure of RV, a-wave and v-wave of right atria curve pressure, calculation of time-constant of RV pressure fall and negative first derivate of RV pressure. Radiofrequency catheter ablation (RFCA) of accessories pathway (AP) has been performed in patents in the main group. RF modulation of AV nodal conduction has been performed in patents in the comparison group.Results
Diastolic dysfunction (DD) of RV has been diagnosed in 49% in patients in the main group by echocardiography and in 100% during invasive hemodynamic study. DF recovered after RFCA of AP. There is no RV DD in the patients in the comparison group.Conclusion
In 49% patients with WPW DD of RV because abnormal ventricular excitation on the AP. DF of RV can be normalized because normalization RV activation after RFCA of AP.