P203Triglicerid level, atherosklerosis of the carotid arteries and inflammation in patient with coronary heart disease in combination with nonalcoholic fatty liver disease

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Abstract

Objective: To compare the relationship of triglyceride levels with atherosclerosis of the carotid arteries and inflammation.

Methods: We studied 25 patients with stable coronary artery disease in combination with nonalcoholic fatty liver disease (NAFLD) (group A) and 21 patients without a NAFLD (group B), mean age 59±6. Patients with diabetes were excluded. We studied biochemical parameters: triglycerides (TG), C-reactive protein (CRP). All patients underwent ultrasound imaging of carotid arteries.

Results: The mean value of TG were 2,95±0,21mmol/l in a group A and 1,54±0,34mmol/l in a group B (p<0,001); of CRP: 1,55±0,21mmol/l and 0,86±0,12mmol/l (p<0,001). Frequency of exposure of atherosclerotic carotid plaques in a group A – 80%, was higher than in a group B – 65%. (p<0,05); There was correlation between the level of TG and degree of stenosis of vessels (r=0,64, p<0,05) and level of CRP (r=0,63, p<0,05) in a group A however in a group B such connection was not observed.

Conclusion: In group A the value of TG were more expressed (r=0,50, p<0,05) than in group B. There was an association between the increase of TG, CRP and degree of stenosis of carotid vessels of head in patients with coronary heart disease in combination with NAFLD.

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