P431Evaluation of tpe-te interval and tpe-te/QTc ratio in patients with coronary artery ectasia

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Aim: Coronary artery ectasia (CAE) is commonly defined as local or generalized dilatation of a coronary vessel up to 1,5 times the diameter of an adjacent vessel. Tp-Te interval and Tp-Te/QT ratio have emerged as a novel electrocardiographic (ECG) markers of increased dispersion of ventricular repolarization. The aim of this study was to evaluate ventricular repolarization by using Tp-Te interval and Tp-Te/QT ratio in patients with CAE.

Materials and methods: Patient records were retrospectively analyzed. ECG of 28 patients, who were diagnosed as CAE were obtained and scanned.Tp-Te, QT and corrected QT intervals and some other ECG intervals were measured. ECGs of age and sex matched 22 healthy control individuals were also analyzed for comparison.

Results: Baseline characteristics and QT, QTc intervals were similar in both group. Tp-Te (97,71±8,7 vs 85,23±7,1; p<0,001) and Tp-Te/QT (0,22±0,0 vs 0,20±0,0; p<0,001) were significantly worse in CAE group.

Conclusions: :Tp-Te is a measure of transmural dispersion of repolarization in the left ventricle and accepted as a surrogate for increased ventricular arrhythmogenesis risk. Tp-Te and Tp-Te/QT are relatively new markers which also indicate repolarization defects. Our results show that CAE patients significantly higher values of Tp-Te and Tp-Te/QT than controls. These measurements may indicate increased arrhythmogenesis risk for individuals with CAE.

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