Plasmodium bergheiANKA infection results in exacerbated immune responses from C57BL/6 mice displaying hypothalamic obesity

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Abstract

Graphical abstract

MSG-obese mice infected with Plasmodium berghei ANKA produce high levels of pro inflammatory cytokines that could be activating leukocytes, leading to parasite elimination by itself or with other unknown mechanisms. However, this strong inflammatory process might be inducing brain damage and mice death. Dashed black arrow represents unknown mechanisms. Dashed red arrows represent hypothetical effects.

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