Experimental models of colorectal cancer

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Abstract

PURPOSE:

A review of in vivo and in vitro models of colorectal cancer is presented.

METHODS:

A retrospective literature review was performed with reference to CD-ROM Medline and Index Medicus.

RESULTS:

A comparison of the advantages and disadvantages of the models is presented in addition to a summary of individual model methodology and applications.

CONCLUSIONS:

Such models are a useful adjunct for surgical research in colorectal oncology.

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