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Radicular groove is an anatomical malformation often predisposing to a severe periodontal defect. Treatment of such an anomaly presents a clinical challenge to the operator. Presented is a case of successful treatment of a radicular groove associated with a maxillary lateral incisor in a 15-year-old girl. A combination of endodontic, intentional replantation and Emdogain® therapy was used. At 1-year follow-up, the patient was comfortable and active healing was evident.