Unusual Microbial Organisms Seen in Two Cervical Smears

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Very infrequently, unusual microbial organisms are encountered in routine cervical Pap tests. We herein report two such cases in two asymptomatic women. Case 1. A Pap smear of a 16-yearold-female showed rare glandular cells with cytologic features consistent with Cytomegalovirus infection. Case 2. A Pap smear of a 36-year-old female exhibited rare fungal organisms characterized by thin septate hyphae branching into secondary branches (metulae) which carried multiple flask-shaped philiades most consistent with Penicillium species that were “most likely representing contamination.” We discuss the cytomorphological features and the differential diagnosis and provide a brief review of the literature on these topics.

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