Choosing the best therapy for treating urinary incontinence in children depends on its cause

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Paediatric incontinence may have a functional or organic aetiology. Anticholinergics that block the muscarinic receptors are widely used to treat overactive bladder, but may be associated with problematic adverse effects. Enuresis cannot be cured pharmacologically, but its symptoms can be managed with a variety of agents. New agents focus on improving muscarinic receptor selectivity, targeting different sites and utilising new drug delivery systems

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