Zonisamide: an effective adjunctive therapy for the treatment of adults with refractory partial epileptic seizures


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Abstract

Zonisamide is a new-generation, broad-spectrum antiepileptic drug (AED), which is chemically unrelated to other AEDs. In pivotal studies, zonisamide was effective as an add-on treatment for adults with partial epileptic seizures unresponsive to monotherapy or combination therapy with other AEDs. It has favourable pharmacokinetic and tolerability profiles and a low potential for drug interactions

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