Consider potential alterations in drug metabolism and excretion when selecting antiepileptics in patients with renal or hepatic impairment

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The choice of which antiepileptic drug (AED) to use in individual patients is challenging, especially in patients with co-morbid renal or hepatic impairment. The individual's degree of renal or hepatic impairment influences the initial selection of AEDs, and may necessitate changes in existing AED treatment.

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