Use NSAIDs to relieve pain and stiffness in patients with ankylosing spondylitis and reserve tumour necrosis factor-α antagonists for NSAID-refractory patients

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Initial pharmacological treatment of ankylosing spondylitis should comprise NSAIDs for the relief of pain and stiffness. Drugs in the NSAIDs class have similar efficacy in relieving pain and improving function in ankylosing spondylitis.

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