Pharmacotherapy can be useful in treating peripheral arterial disease, but options are limited

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Effective pharmacological options for peripheral arterial disease are limited. For intermittent claudication that persists despite exercise training, cilostazol is the first-line therapy and pentoxifylline is a second-line option, while the agents potentially useful for critical limb ischaemia when revascularization is unsuitable include cilostazol and prostaglandins. Cardiovascular risk factors should be modified in all patients.

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