Adjust therapy for restless legs syndrome if symptoms worsen, efficacy is lost or iatrogenic augmentation develops

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Abstract

Restless legs syndrome (RLS) is a common sensorimotor disorder that frequently requires long-term treatment. Although dopamine agonists are commonly used to treat RLS, their long-term use is often complicated by worsening symptoms, loss of efficacy and augmentation (an iatrogenic worsening of RLS symptoms). It is important to consider various factors that can exacerbate RLS, and to implement treatment strategies to prevent and manage these complications.

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