Does calcium with vitamin D prevent postmenopausal fractures?

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Evidence-Based Answer

Calcium supplementation is associated with a reduced incidence of osteoporotic fractures in older postmenopausal women. Calcium doses of 1,200 mg and 80% or higher compliance increase the benefit. Vitamin D does not add to the benefit over calcium alone and increases the risk of hypercalcemia, renal calculi, and renal insufficiency (SOR: A, meta-analyses).

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