What is the most effective therapy for immunocompetent infants with oral thrush?

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Evidence-Based Answer

Oral fluconazole (3 mg/kg per day) and ketoconazole (20 mg TID) are more effective than nystatin suspension (SOR: B, small and unblinded RCTs). Gentian violet is also more effective than nystatin, but can stain clothes and skin and can cause mucosal ulcerations (SOR: B, small retrospective cohort study).

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