What is the incidence of acute rheumatic fever in untreated children withStreptococcuspharyngitis?

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Abstract

Evidence-Based Answer

Prior to the antibiotic era, the incidence of acute rheumatic fever was 28.5 cases per 100,000 children (SOR: C, retrospective study). Since the advent of antibiotics, the incidence of acute rheumatic fever has declined and is as low as 3.7 per 100,000 people in some parts of the United States (SOR: C, retrospective study).

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