Should you treat an upper extremity DVT with anticoagulation?

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Evidence-Based Answer

Treatment of upper extremity deep-venous thrombosis (UEDVT) for 3 months appears to resolve the thromboembolism and has similar outcomes compared with lower extremity DVT treatment. Patients with cancer tend to have higher incidence of adverse outcomes such as major bleed or recurrent DVT (SOR: B, cohort trial). Guideline recommendations include acute parenteral anticoagulation and then transitioning to oral therapy for 3 months (SOR: B, evidence-based guideline).

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