Can HbA1C be used to predict which patients are at risk for developing type 2 diabetes mellitus?

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Glycosylated hemoglobin (HbA1C) 5.3%-6.4% has a similar predictive value to fasting plasma glucose (FPG) >99 mg/dL over 5 to 6 years; an abnormal result on both measures is more predictive of developing type 2 diabetes mellitus (DM2) than an abnormal result on either test alone (SOR: C, consistent cohort studies of disease oriented outcomes).

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