What is the best therapy for exerciseinduced asthma in adults?

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Abstract

EVIDENCE-BASED ANSWER

The answer is unclear. A single dose of either a short- or long-acting beta-agonist improves forced expiratory volume in 1 second (FEV1) (SOR: C, meta-analysis of crossover and cohort studies with disease-oriented outcomes), but long-term regular use of either class of agent may induce tolerance and decrease efficacy in exercise-induced asthma (SOR: C, expert opinion). Montelukast or fish oil appear to decrease bronchodilator use and improve postexercise FEV1 (SOR: C, single small RCT).

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