In patients with uterine bleeding due to a progestin contraceptive implant, are combined oral contraceptives (COCs) helpful?

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EVIDENCE-BASED ANSWERShort-term (14–20 days) use of COCs reduces bleeding days and time to cessation of bleeding in implant users; however, bleeding reoccurs quickly after cessation of COC treatment (SOR: B, small RCTs). COCs are not recommended for routine treatment of irregular bleeding (SOR: C, expert opinion).

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