In patients with acute gouty attacks, should allopurinol be started immediately or delayed?

    loading  Checking for direct PDF access through Ovid



Starting allopurinol immediately may not have large adverse effects on duration, severity, or recurrence of acute gouty attacks (SOR: B, limited-quality noninferiority RCTs). In patients who are candidates for allopurinol, allopurinol 100 mg daily may be started with colchicine 0.6 mg BID at the onset of an acute flair, with a goal of titrating allopurinol up after 2–5 weeks (SOR: C, consensus guideline).

Related Topics

    loading  Loading Related Articles