Should the varicella-zoster virus be given to all children to prevent chicken pox?

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EVIDENCE-BASED ANSWERThe administration of the varicella vaccination to healthy, nonimmunized children greatly decreases the incidence of varicella (SOR: B, double-blind placebo-controlled efficacy trial). Such vaccination has resulted in an 87% reduction in varicella-related mortality. The use of the vaccine in immunocompromised children has not been approved by the US Food and Drug Administration.

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