What is the best therapy for anal fissures?

    loading  Checking for direct PDF access through Ovid



Surgical management is consistently superior to topical diltiazem or glyceryl trinitrate for chronic anal fissure (SOR: A, systematic review and meta-analysis) and perhaps also for acute anal fissure (SOR: C, small cohort study). Among medical therapies, diltiazem 2% ointment and glyceryl trinitrate 0.2% ointment are equally effective, but diltiazem has a 30% lower recurrence rate and a 60% lower incidence of headache (SOR: A, systematic review of RCTs).

Related Topics

    loading  Loading Related Articles