In adults with community-acquired pneumonia (CAP), are corticosteroids beneficial?

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Abstract

EVIDENCE-BASED ANSWER

Yes. In patients with severe CAP, corticosteroids reduce mortality, length of hospital stay, need for mechanical ventilation, development of adult respiratory distress syndrome (ARDS), and time to clinical stability (SOR: A, meta-analysis of RCTs). Corticosteroids show better efficacy in patients with severe CAP and septic shock than in patients with CAP but no shock (SOR: B, large cohort study).

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