In adults with community-acquired pneumonia (CAP), are corticosteroids beneficial?

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Yes. In patients with severe CAP, corticosteroids reduce mortality, length of hospital stay, need for mechanical ventilation, development of adult respiratory distress syndrome (ARDS), and time to clinical stability (SOR: A, meta-analysis of RCTs). Corticosteroids show better efficacy in patients with severe CAP and septic shock than in patients with CAP but no shock (SOR: B, large cohort study).

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