Are anticonvulsants effective for treating alcohol dependence?


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Abstract

EVIDENCE-BASED ANSWERAnticonvulsants as a class do not increase abstinence but do decrease heavy drinking and drinks per drinking day by about 1.5 (SOR: A, meta-analysis of RCTs). Gabapentin (SOR: B, RCT) and topiramate (SOR: C, small RCT) may increase abstinence rates.

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