Is acetaminophen safe to use in patients with cirrhosis?

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Abstract

EVIDENCE-BASED ANSWER

Maybe. Acetaminophen use of 2 to 3 g/d for an average of 2 to 3 days or 1 g/d for 25 days in cirrhotic patients is not associated with an increased risk of hospitalization for acute liver decompensation (SOR: C, 2 case-control trials).

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