Is aspirin effective in preventing maternal or fetal complications in pregnant women with mild to moderate chronic hypertension?

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EVIDENCE-BASED ANSWERNo studies have directly evaluated the effect of aspirin in pregnant women with chronic hypertension only. However, in women with risk factors for preeclampsia, including chronic hypertension, low-dose aspirin administered after the first trimester of pregnancy reduces the risk of preeclampsia, intrauterine growth restriction, preterm birth, and fetal or neonatal deaths (SOR: A, meta-analyses of RCTs).

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