Update on the Role of Substantia Nigra Pars Reticulata in the Regulation of Seizures

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The substantia nigra pars reticulata (SNR) represents an endogenous seizure suppressing system, which may be targeted to develop treatments for generalized or multifocal epilepsies. This review summarizes the region-, age-, and sex-specific features of the SNR-based seizure-controlling network.

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