Vascular lesions are benign lesions that are common in the head and neck. They can cause esthetic, functional, and psychological impairment. The most common site is the tongue. Treatment is primarily dependent on correct diagnosis of the lesion and on its anatomic location. The aim of this study was to use ethanolamine oleate in the management of vascular lesions in the oral region. Precise diagnosis and appropriate therapeutic management resulted in satisfactory esthetic and functional results, with complete resolution of the lesion and no sign of relapse at 6 months of follow-up.