Metabolic syndrome and gender differences in postprandial lipaemia

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Abstract

Background

Postprandial hyperlipidaemia may be a predictor of vascular risk.

Design

We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).

Methods

Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.

Results

Men showed a greater plasma TG response 8 h after the fat load (284±117 versus 224±126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.

Conclusions

Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.

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