Morbidity and mortality following poliomyelitis – a lifelong follow-up

    loading  Checking for direct PDF access through Ovid

Abstract

Background and purpose:

In the world today 10–20 million people are still living with late effects of poliomyelitis (PM), but the long-term consequences of the disease are not well known. The aim of this study was to describe lifelong morbidity and mortality among Danes who survived PM.

Methods:

Data from official registers for a cohort of 3606 Danes hospitalized for PM in the period 1940–1954 were compared with 13 762 age- and gender-matched controls.

Results:

Compared with controls, mortality was moderately increased for both paralytic as well as non-paralytic PM cases; Hazard Ratio, 1.31 (95% confidence interval, 1.18–1.44) and 1.09 (95% confidence interval, 1.00–1.19), respectively. Hospitalization rates were approximately 1.5 times higher among both paralytic and non-paralytic PM cases as compared with controls. Discharge diagnoses showed a broad spectrum of diseases. There were no major differences in morbidities between paralytic and non-paralytic PM cases.

Conclusions:

Poliomyelitis has significant long-term consequences on morbidity and mortality of both paralytic and non-paralytic cases.

Related Topics

    loading  Loading Related Articles