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Forty extracted maxillary incisors were decoronated, prepared in a crown-down fashion and randomly divided into two groups of 16 roots each. Remaining roots served as controls. Smear layer was removed with 17% EDTA followed by 5.25% NaOCl, the canals in group N were again rinsed with NaOCl before obturation with laterally compacted gutta-percha and Roth's 801 sealer. The roots in group E were rinsed with 95% ethyl alcohol instead of NaOCl for the final rinse. Leakage was determined using a fluid-flow model. Roots were cleared, split, and sealer penetration into the dentinal tubules was measured under light-microscopy. Group E demonstrated significantly greater sealer penetration (p = 0.002) and significantly less leakage (p = 0.040), than group N. Leakage could not be significantly correlated with sealer penetration (p = 0.725). Under the conditions of this study, we found that a final rinse with 95% ethyl alcohol increased sealer penetration and decreased leakage.