Bubble trouble: anaphylactic shock, threatened myocardial infarction, and transient renal failure after intravenous echo contrast for left ventricular cavity opacification preceding dobutamine stress echo

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Echo contrast agents are widely used and safe but can rarely produce serious side effects. This—to the author's knowledge—is the first detailed published case report of a patient who had a severe and complex sequence of adverse reactions within 3 min of having an intravenous infusion of Sonovue initiated, and where the causal connection between Sonovue and the adverse reaction is not diluted by potential side effects from dobutamine.

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