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During the last decade tissue Doppler and myocardial deformation imaging has been introduced to quantify myocardial function in patients with congenital heart disease. These methods could have potential benefits for patients where the anatomy makes it difficult to quantify ventricular function using M-mode or two-dimensional volumetric techniques. In this overview, the potential benefits as well as limitations of the techniques are discussed. Looking directly into the myocardium renders the techniques geometry-independent, allowing the quantification of right ventricular as well as univentricular systolic function. The limitations include the influence of variable loading conditions as well as different methodological problems.