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The aim of the study was to evaluate the sensibility and the specificity of a handheld ultrasound scanner compared to a standard machine in assessment of routine patients.Methods: 32 consecutive patients (mean age 68±12 years, 18 women) referred for routine echocardiography in a cardiology department underwent examinations with a handheld ultrasound scanner (HHUS) (2D and color doppler) and a high-end standard ultrasound scanner(SDUS). We assessed the sensibility and specificity of the handheld device for chambers size quantification, severity of regurgitations and valve abnormalities.Results: the sensibility and specificity of HHUS used to detect wall hypertrophy was 99% and 73%. The corresponding values for chamber dilatation were 100 % and 85 % dilatation, with 95% CI:0,78-1. Severe mitral regurgitation was identified with a sensibility of 100% and specificity of 84% with 95%CI: 0,74-1, respectively 92% and 78% for aortic regurgitations. Valve defects were identified by HHUS with a specificity of 87% for the aortic valve and 89% for the mitral valve while the sensibility was 62% respectively 67%.Conclusion: HHUS is an efficient tool for the identification of chambers size abnormalities. Valve abnormalities were identified in a lesser degree and needed standard scanning for complete assessment.