|| Checking for direct PDF access through Ovid
Purpose: Transcatheter aortic valve implantation (TAVI) provides a model for studying left ventricular (LV) adaptation to abrupt afterload decrease in a setting without pericardiotomy or cardioplegia.Methods: 19 patients (6 men, 82±6 years) were studied one day before and 5 days after TAVI of CoreValve prosthesis, using conventional and speckletracking echocardiography. In parasternal short axis (PSAX) an imaging plane apical to the base of the papillary muscles was used for circumferential and radial deformation and for rotation. Apical 4-chamber was used for longitudinal deformation analysis.Results: Abrupt relief of severe aortic stenosis was followed by increased systolic strain rate, both circumferentially and radially in parasternal short axis and longitudinally in apical 4-chamber.Systolic strain and rotation were not significantly increased (cfr Table). Change in heart rate or blood pressure did not correlate with and could not explain changes in any of the deformation variables.Conclusions: Systolic function early after TAVI was characterized by increased strain rate reflecting a more rapid contraction.