P352Determination of the subclinical systolic dysfunction with the speckle echocardiography method in obstructive sleep apnea syndrome patients with normal ejection fraction

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Purpose: We aimed to determine the subclinical systolic dysfunction in obstructive sleep apnea syndrome (OSAS) patients with normal EF (ejection fraction).Method: 21 controls (G0) and 58 patients with normal EF (ejection fraction); according to the apnea-hypopnea indices (AHI); mild (AHI=5-15/G1), moderate (AHI=15-30/G2), severe (AHI>30)/G3) were included.Standart echocardiography and STE (speckle tracking echocardiography) performed.The average values of all segments were calculated and expressed as the global values.Results: The global longitudinal strain (GLS) impairment begins in the G2,the global radial (GRS) and circumferential (GCS) impairment starts in the G3. When compared with the G0, the GRS values are increased in the group 1 and 2 without statistical significance. The global systolic strain rates of the longitudinal fibers (GL-S-SR) and circumferential fibers (GC-S-SR) were began to decrease in the G2. The global radial systolic strain rate (GR-S-SR) was higher in G2 than the G0 but it was decreased in G3 (Table-1).Conclusion: In early stages of OSAS, the longitudinal systolic dysfunction is compensated with the aggravated radial fiber function.However in this stage, the circumferential systolic function does not change. In severe OSAS patients, besides the diastolic dysfunction the all myocardial fibers have also systolic function impairment; the longitudinal and circumferential mechanics are influenced more than the radial function.

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