P434Right ventricle impairment and left ventricle global function in heart failure patients with systolic dysfunction.


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Abstract

Introduction: Right ventricle (RV) dysfunction in heart failure patients due to left ventricle systolic impairment has a worst prognosis.Objective: Evaluate the relationship between RV systolic function and the LV global function in patients with LV systolic impairment heart failure.Methods: 100 pts (60% M), age 72.5±10 years old regularly followed in a heart failure clinic, ejection fraction (EF) of the LV 30.78±9.5%, cardiac output (CO) 4.25±1.59, Nt-ProBNP median 1337.0 pg/ml, LV end diastolic diameter 6.82±0.97 cm. RV systolic function characterized by the TAPSE, tricuspid TDI S, RVEF and RV longitudinal strain (GS). LV global function: LV longitudinal global strain (GS) and strain rate (GSR), mitral TDI, and CO. Relationship between parameters evaluated with Spearman correlation coefficient and linear regression model (backward method).Results: Table 1 represents the correlation between RV systolic function and LV systo diastolic function. There is a significant correlation between all RV systolic parameters and the LV global function. Lower the TAPSE, Tr-S and RV-EF worst the LV cardiac output and LV longitudinal contractility. Mt-A and LV-GSRa marked important LV diastolic impairment with lower RV systolic function.Conclusion: RV systolic dysfunction in heart failure patients is associated with LV systolic and diastolic dysfunction, what could explain the worse prognosis in this subgroup of patients

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