P447Normal myocardial strain values by speckle tracking echocardiography in patients in the first year post-heart transplantation in the absence of acute cellular rejection.


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Abstract

Introduction and objectives: Our objective is to describe normal values of myocardial strain in the first year post-heart transplantation measured by means of bidimensional speckle tracking echocardiography (2DSTE). Method: From September 1st, 2009 to November 30th, 2010 we have performed an exhaustive echocardiographic exam (iE33, Philips) in all transplant recipients in their first post-transplantation year within 5 hours of the routine survaillence endomyocardial biopsies. We selected for this analysis all those exams that were coincident with no acute cellular rejection (grade 0). Radial and circumferential peak strain of the left ventricle at the level of papillary muscles short axis view and longitudinal peak strain of the left and right ventricles at the apical four chambers view, evaluated by means of 2DSTE, were obtained in all of them.Results: Out of 73 studies performed 4±3 months after heart transplantation in 18 patients (mean age 51±16 years, 83% male), 30 were coincident with absence of acute cellular rejection (grade 0). Peak strain values are shown in the table.Conclusion: To our knowledge, this is the first study describing normal values of myocardial strain by 2DSTE in heart transplant recipients in the first year after the procedure, with histologically proven absence of rejection at the moment of the evaluation.

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