P652Comparison of indexing methods in predicting left ventricular hypertrophy and mass index in overweight and obese persons.


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Abstract

Purpose: The purpose of the study was to compare the different indexing methods in determining left ventricular (LV) mass index in obese persons.Methods: Eighty-one obese patients (49 women, 32 men, mean age 47.6± 12.3 years, mean body mass index 46.9± 7.7 kg/m(2), mean weight 138± 28 kg) were enrolled in this study. LV mass was detected by transthoracic echocardiography with linear method. LV mass was indexed by three different methods: LV mass/body surface area (BSA) (g/m(2)), LV mass/height (g/m) and LV mass/height (g/m(2.7)). The results were compared to the normal values recommended by the American Society of Echocardiography and European Association of Echocardiography. To compare differences between the groups Fisher's exact test was used.Results: When LV mass was indexed to mass/BSA (g/m(2)) 50 patients out of 81 patients (50/81, 62%) were classified as normal and 31 patients (31/81, 38%) as abnormal. When LV mass was indexed to mass/height (g/m) 12 patients (12/81, 15%) were classified as normal and 69 patients (69/81, 85%) as abnormal. When this was compared with indexing to mass/BSA, the difference between these two methods was statistically significant (p<0.0001). When LV mass was indexed to mass/height(2.7) (g/m(2.7)) 16 patients (16/81, 20%) were classified as normal and 65 patients (65/81, 80%) as abnormal. When this was compared with indexing to mass/BSA, the difference between these two indexing methods was statistically significant (p<0.0001).Conclusions: LV mass should always be indexed also to mass/height or mass/height(2.7) in overweight and obese persons.

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