P654Relationship between systolic intra-ventricular pressure and global longitudinal function;effect of load conditions.


    loading  Checking for direct PDF access through Ovid

Abstract

Behaviour of peak systolic intra ventricular presure gradient (SIVPG), which depends on inertial and convective forces, is comparablewith that of dp/dt. Global longitudinal strain (GLS) is now considered as a surrogateof LV systolicfunction (EF). The aim of this study was to evaluate therelationship betwwen SIVPG and the GLS and the effect of preload and afterloadparameters on this two variables.Methods: One hundred consecutive patients were enrolled in this study unreceptivelyof the clinical status. Mean age was 55.8 ± 18.1. On top of regular echo parameters evaluatingpreload, afterload and global LVfunctiin, the following parametes were acquired. Arterial elastance (Ae),single beat end systolic elastance (Ees), Global longitudinal strain, and SIVPG(calculated from M mode color Doppler according to the Euler equation).Results: Impact of preload and afterload parameters on GLS and SIVPG isshown on table 1. GLS correlate significantly with SIVPG (y = -14,22 + -0,54 x,r=-0.49; p<0.001). Sub group of patient with SIVPG< 8 mmHg have lowerGLS values compared to patient with SIVPG > 8 MMhG (-17.3 ±3.3, vs –19.8±3.0;p=0.0003)Conclusion: GLS is affected by pre and after load conditions and is significantlycorrelated to the systolic IVPG. In opposition this study confirms that SIVPGis relatively independent of loading conditions.

    loading  Loading Related Articles