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Purpose: Speckle tracking is a new simple echocardiographic method to assess left ventricular (LV) strain, rotation and torsion. The aim of the present study was to investigate the effects of acute anterior myocardial infarction (AMI) on LV torsional, rotational and strain parameters.Methods:In 21 healthy pigs myocardial infarction was performed by occlusion of the left anterior descending coronary artery (LAD). LV torsion was calculated by measuring LV basal and apical rotation. Moreover, radial and circumferential deformation and their peak systolic rate were measured from basal and apical short-axis epicardial planes with speckle tracking technique using EchoPAC platform. All parameters were evaluated before and 30 min post LAD ligation.Results: TableConclusion:LV systolic torsion is impaired in AMI, possibly as a result of diminished LV function and reduced rotational and deformation parameters of LV apex.Speckle-tracking imaging may be suitable for noninvasive evaluation of LV function of ischemic heart disease.