P952Left ventricular strain by indexed motion mode - normal values according to age and sex


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Abstract

Purpose: Longitudinal indices of left ventricular (LV) function have been shown sensitive to detect and quantify LV dysfunction. Mitral annular excursion (MAE) by apical m-mode is an attractive measure as there is little need of post-processing compared to more advanced longitudinal LV strain. By indexing MAE (iMAE) by LV length a measure that corresponds to global strain is obtained. We aimed to establish normal values for indexed mitral annular excursion according to age and sex.Methods: 1296 persons (20-89 years) which participated in the HUNT 3 study were randomised to echocardiography. Participants were eligible for inclusion if they were free from known heart diseases, diabetes or hypertension. 30 were excluded from further analyses after detection of moderate to severe pathology during echocardiography. The study participants were stratified according to age (<40, 40-59, and ≥60 years) and sex.Mitral annular excursion (MAE) were measured by m-mode at the base of the lateral, septal, anterior and inferior wall and indexed according to length of each wall (apical epicardium to mitral annulus) into iMAE. Presented iMAE and MAE are average of the four walls.Results: Feasibility was >99%. Table (below) shows preliminary normal values for MAE and iMAE according to age and sex from a sub population of 454 participants.MAE and iMAE was lower with increasing age (p<0.001). iMAE was higher in women than in men. (Table).Conclusions: Normal values for indexed mitral annular excursion are presented according to sex and age. In line with previously publications on other longitudinal indices of LV function there is a clear reduction by higher age, and some differences between sexes as well. MAE and iMAE by m-mode are attractive due to the low demand of post processing.Abbreviations: LV; left ventricle, MAE; mitral annular excursion

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