P953Repeatability of echocardiographic measures of left ventricular function in the paediatric cardiology out-patient clinic setting

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Purpose: Tissue Doppler imaging(TDI) and speckle tracking(ST) techniques are increasingly used in the clinical setting despite their uncertain reliability in children. Our aim was to assess the repeatability of TDI, ST and 2D echo(2DE) assessments of LV function in children attending cardiology out-patient clinic.Methods: Scans were performed using a Philips IE33 scanner with S5 probe. LV ejection fraction (LVEF) was assessed from the apical 4-chamber and basal short axis views (5/6 area-length). Pulsed wave TDI of interventricular septum(IVS) and LV free wall(LVFW) and ST analysis were performed from the apical 4-chamber view. Repeat views were obtained by the same technician during the clinical assessment and analysed (Philips QLab) blinded to the initial scan data. Scan-rescan repeatability was assessed using Bland-Altman limits of agreement (LOA) and repeatability index (LOA/mean) to compare different techniques.Results: 20 children median(range) 15(7-19) years having a routine echo for hypertension(n=7), cardiomyopathy(n=7) or sickle cell disease(n=6) were studied. Number of subjects, population means, and repeatability measures are given in the table.Conclusions: TDI assessments of LV longitudinal motion appear to have superior scan-rescan repeatability to traditional ejection fraction measures in the paediatric population. Speckle tracking measures of LV function appear to be less repeatable, but may still have utility due to the additional functional analysis available.

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