P961Evaluation of left ventricular diastolic reserve in hypertensive patients using stress echocardiography

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Purpose: To evaluate diastolic function parameters in hypertensive patients, to determine changes of these parameters after exercise, and the diastolic parameters before and after exercise comparison with effort capacity.Method: Fifty hypertensive patients (mean age 51.0±8.96, 58%men) were included in the study. Patients who have diabetes mellitus, abnormal sinus rhythm, coronary artery disease, moderate-to severe valvular regurgitation/stenosis, prosthetic valve and renal failure were excluded from the study. After the evaluation of patients echocardiography in rest, diastolic function parameters were measured after exercise and compared with the results in rest.Results: Early diastolic flow velocity (E) was significantly higher after exercise compared to rest (0.76±0.11 m/s vs 0.91±0.14 m/s, p<0.0001), whereas there was no statistically significant differences between late diastolic flow velocities (A) (0.75±0.14 m/s vs 0.75±0.18 m/s, p=0.77). Mitral diastolic flow E/A ratio was found significantly increased with exercise (0.99±0.34 vs 1.34±0.55,p<0.0001). There was a significant relationship between Borg index and E/e' values which was measured in rest (r=0.285, p=0.001). Similarly, significant correlation was found between E/e' ratio after exercise (r=0.372, p=0.001)(Figure-1).Conclusion: The ratio of early diastolic transmitral velocity to early diastolic tissue velocity correlates with dyspnea index in hypertensive patients. Diastolic stress test is an easy test to apply in clinical practice and helps the physician to explain the dyspnea in hypertensive patients who have normal or slightly diastolic dysfunction.

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