Tooth Loss May Be More Frequent in Older People With a Genetic Predisposition Towards Dementia

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ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATIONTooth loss, dementia and neuropathology in the Nun Study.Stein, P. S., M. Desrosiers, S. J. Donegan, J. F. Yepes and R. J. Kryscio (2007).J Am Dent Assoc 138(10):1314-22; quiz 1381-2.LEVEL OF EVIDENCELevel 2 (Limited-quality, patient-oriented evidence)STRENGTH OF RECOMMENDATION GRADENot applicablePURPOSE/QUESTIONThe authors wished to identify any statistical relationships between the number of remaining teeth and both the prevalence at baseline and autopsy and the incidence of dementia and in a cohort of older nuns over a 12 year period.SOURCE OF FUNDINGNational Institute of Aging (US) with additional funding from NIH and two research foundationsTYPE OF STUDY/DESIGNObservational retrospective cohort study plus cross-sectional analysis

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