The 11th hour-time for EBM to return to first principles?
Payer decision-making with limited comparative and cost effectiveness data
Robustness, risk and responsivity in early language acquisition
Caudal epidural steroid injections no better than saline epidurals or sham injections for the treatment of chronic lumbar radiculopathy
Some oral antidiabetic medications may prevent Type 2 diabetes in people at high risk for it, but the evidence is insufficient to determine whether the potential benefits outweigh the possible risks
Oral ondansetron decreases vomiting, as well as the need for intravenous fluids and hospital admission, in children with acute gastroenteritis
In irritable bowel syndrome, antispasmodics and antidepressants improve abdominal pain and global assessment and symptom scores, but there is no evidence for the effectiveness of bulking agents
In TIA or stroke patients with intracranial arterial stenosis, aggressive medical therapy was superior to percutaneous transluminal angioplasty and stenting for 30-day risk of further stroke or death
Evening dosing of antihypertensive medications results in better blood pressure control and decreases cardiovascular morbidity and mortality in patients with Type 2 diabetes
Population benefits of HPV vaccination for boys
Greater diabetes-care contact frequency is associated with more rapid achievement of care goals but interpretation of finding requires consideration of patient adherence and motivation
Preterm birth, a known risk factor for infant and childhood death, is an independent risk factor for mortality in early childhood and young adulthood
Cardiovascular risks of stopping antiplatelet therapy before non-cardiac surgery for patients with coronary stents
Early introduction of allergenic food is not associated with increased report of wheeze or eczema
Breastfeeding by mothers infected with hepatitis B carries no increased risk of transmission to infants who receive proper immunoprophylaxis
Breast feeding is associated with decreased risk of sudden infant death syndrome
Positive parenting in adolescence is associated with well-(adaptive-) functioning adult offspring
Observational studies find association between chocolate consumption and reduced risk of cardiovascular disease and diabetes
Exposure to trimethoprim–sulfamethoxazole is associated with hospitalisation for hyperkalaemia in older people treated with spironolactone
Non-fasting blood testing for lipid screening in children result in statistically significant, but not clinically significant, changes in lipid levels
Purpose and procedure