Why we need more breast cancer screening trials
Thiazolidinediones for plaque psoriasis
Acute conjunctivitis in primary care
In patients with coronary artery disease and heart failure, the addition of coronary-artery bypass grafting to medical therapy has no effect on the overall risk of death from any cause, but assessment of suitability for surgery may predict survival benefit in subgroups
Early umbilical cord clamping increases the risk of neonatal anaemia and infant iron deficiency
For people with persistent tension-type neck pain, a multicomponent pain and stress self-management intervention gives better improvement in ability to control pain and self-efficacy, but not disability, than physical therapy
Catheter-directed thrombolysis prevents post-thrombotic syndrome in patients with acute deep vein thrombosis in the upper half of the thigh
The legacy effect
Combined vitamin D and calcium supplementation may reduce fracture risk in institutionalised older people but has uncertain role in cancer prevention
Study of the effect of calcium supplementation during pregnancy on the risk of preterm birth or low birthweight infants is inconclusive
Nicotine replacement therapy increases quit attempts among unmotivated smokers when added to encouragement to practice quitting
Forty-month trial suggests repeated hyaluronic acid injections for people with knee osteoarthritis may act as a long-term slow acting drug
Of 3700 children thought to have non-cardiac chest pain at initial paediatric cardiology clinic evaluation, none suffered cardiac death over a median of 4 years follow-up
Statin use in postmenopausal women is associated with an increased risk of incident diabetes mellitus
Night shift work increases the risk for type 2 diabetes
Screening for postmenopausal osteoporosis with any modality is cost-effective including screening initiation at 55 years of age
Response to Drs Hoberman and Paradise
Is recent advice on exclusive breastfeeding consistent with the data presented?
Purpose and procedure
Higher breastfeeding intensity associated with improved postpartum glucose metabolism in women with recent gestational diabetes
For women with term low-risk pregnancies, risk of perinatal mortality and intrapartum morbidity similar across planned places of birth
In China, hospital births are associated with a 62% decreased risk of neonatal mortality
Serial changes in highly sensitive cardiac troponin improve the early diagnosis of acute myocardial infarction
Children with minor blunt head trauma, a Glasgow Coma Scale score of 14 or 15 and a normal CT scan are at very low risk of traumatic findings on subsequent neuroimaging or of requiring neurosurgical intervention
Low-molecular-weight heparin prophylaxis does not affect mortality in acutely ill medical patients at low risk for venous thromboembolism
Multicondition collaborative care intervention for people with coronary heart disease and/or diabetes, depression and poor control of hypertension, blood sugar or hypercholesterolemia improves disability and quality of life compared with usual care
Self-monitoring of oral anticoagulation reduces thromboembolic events and does not increase risk of bleeding in selected patients and settings
Topical dexamethasone for recurrent aphthous ulceration reduces pain and size and increases healing with no significant adverse events
Antibiotics provide no clinically important benefit in mild to moderate acute sinusitis