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A novel approach to the determination of clinical decision thresholds
An evidence-based approach to an ancient pursuit
Discontinuing inhaled steroids might not be safe in severe COPD cases
Home blood pressure monitoring with patient-initiated drug titration reduces blood pressure in high-risk patients with hypertension
Evidence is weak to support hepatocellular carcinoma screening in chronic liver disease
CALORIES trial offers confirmatory evidence that parenteral nutrition does not cause infectious complications in critically ill patients
Angiotensin receptor-neprilysin inhibitors in heart failure
Bubble CPAP may be safe and efficacious for neonates in low and middle income countries, but more evidence is needed
Penicillin is the drug of choice to treat all stages of syphilis despite a paucity of clinical trials data for the treatment of some stages, pregnant women and HIV-infected people
Tonsillectomy or adenotonsillectomy reduces the number of sore throats in children; however, insufficient information is available on the effectiveness in adults
Meta-analysis compares anticoagulant strategies in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention
The evidence for treating acute pyelonephritis with oral antibiotic therapy and short intravenous treatment is growing for low-risk children
Similar clinical outcomes but more healthcare use in shoulder impingement patients following corticosteroid injection compared with physical therapy
Stricter systolic blood pressure control is associated with higher all-cause mortality in patients with chronic kidney disease
Weight loss ≥10% is required by the severely obese to achieve minimal clinically important differences in health-related quality of life
Breast feeding and timing of introduction of gluten in infant foods are not predictors of coeliac disease at age 5
The ‘surprise’ question may improve the accuracy of GPs in identifying death in patients with advanced stage IV solid-cell cancer
Uncertainty remains about early pregnancy outcomes after treatment for cervical intraepithelial neoplasia
The administration of pertussis vaccine to pregnant women was associated with a small increased risk of chorioamnionitis, but not an increased risk of hypertensive disorders or preterm birth
Maternal overweight and obesity in early pregnancy are associated with an increase in infant mortality risk
Benzodiazepine exposure increases risk of Alzheimer's disease
Transmitting risk effectively in studies is feasible, but insufficient for shared decision-making
Bypass surgery is more cost-effective than percutaneous coronary interventions for most patients with multivessel or left main coronary artery disease
Lung cancer CT screening is cost-effective but implementation matters
Mixed kinds of evidence
Broadening the evidence base and the mind when thinking about mixed methods research