Improving reporting and utility of evaluations of complex interventions
Elucidating the use of enoxaparin in non-ST-elevation acute coronary syndromes (NSTE-ACS)
Formative assessment and design of a complex clinical decision support tool for pulmonary embolism
NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis
Cervical arthroplasty compares favourably to ACDF at half-decade follow-up
Longer dual antiplatelet therapy (DAPT) after percutaneous coronary intervention has higher anti-ischaemic efficacy than shorter DAPT but is associated with more frequent bleeding
Low to moderate quality evidence demonstrates the potential benefits and adverse events of cannabinoids for certain medical indications
Structured diet and physical activity programmes provide strong evidence of effectiveness for type 2 diabetes prevention and improvement of cardiometabolic health
The addition of abdomen and pelvis CT to limited cancer screening does not increase diagnosis of cancer in patients with unprovoked venous thromboembolism
Blood glucose monitoring had no impact on distress or self-efficacy in people with non-insulin-treated type 2 diabetes
Supplemental oxygen in patients without hypoxia in ST segment elevation myocardial infarction increases myocardial injury and infarct size
Tamsulosin and nifedipine did not improve stone passage over placebo nor were they cost-effective in ureteric stone disease
No differences between operative and non-operative treatments of proximal humerus fractures
The effectiveness of a single dose of oral ibuprofen plus caffeine in acute postoperative pain in adults
Dextromethorphan and quinidine are suitable for off-label short-term treatment of agitation in people with Alzheimer's disease following first-line non-drug approaches
Initiating antiretroviral therapy in HIV-infected patients with >500 CD4 cells/µL provides more benefit than delaying treatment
Mechanical bowel preps improve surgical outcomes in colorectal surgery
Early laparoscopic cholecystectomy appears better than delayed laparoscopic cholecystectomy for patients with acute cholecystitis
Elective colectomy for severe ulcerative colitis may reduce mortality more than medical therapy
High-dose vitamin D supplementation does not alter bone mass or muscle function over 1 year in postmenopausal women
Surgery and physical therapy likely yield similar outcomes in spinal stenosis
Annual volume of very low-birth-weight infant deliveries appears to be more important than level of neonatal intensive care unit for optimising perinatal care
ACE inhibitors in African Americans with hypertension associated with worse outcomes as compared to other antihypertensives
Sugar sweetened beverages are associated with greater incidence of diabetes but there is a paucity of evidence on healthfulness of artificially-sweetened beverages and fruit juices
A higher overall diet quality is inversely associated with the risk of chronic obstructive pulmonary disease (COPD) in men and women
Observational studies are compatible with an association between saturated and trans fats and cardiovascular disease
The risk of arterial thrombosis increases with the use of combined oral contraceptives
Thessaly test is no more accurate than standard clinical tests for meniscal tears
A single cervical length measurement at 18–24 weeks is a better predictor of preterm birth than the change in cervical length with gestation